陈慎宝; 丁如宁
南京医科大学微生物学教研室!南京210029; 南京医科大学微生物学教研室!南京210029

【中文摘要】 中国古代著名药用菌槐耳（Trametes robinpphila Murr.）在营养基质上进行固体发酵,产生槐耳菌质,从中提取的清膏及进一步提取的蛋白多糖,都有显著的抑制动物体内瘤和延长生命等作用,抑癌率可达50％左右.清膏治疗中晚期原发性肝癌总有效率达75.71％,它们具有促进多种免疫功能的作用,是良好的生物反应调节剂（BRM）,并有可能进一步扩大其适应症.

【英文摘要】 Through solid fermentation in nutrient substratum, Trametes robiniophila Murr. (TRM), used as a famous medicinal fungi in ancient china, produced fungal substance from which clear paste and further isolated proteoglycan had been extracted. Both clear paste and proteo'glycan had tumor-inhibition effect on experimental animals and prolonged the life of infected animals And the tumor inhibition rate ia about 50%. Patients with middle or later period primary hepatoma treated with the paste, had got a total efficient rate of about 75%. Both the TRM clear paste and the proteoglycan promoted various immune functions. They are good biological response modifier and may be used to treat other adaptive diseases.

【中文关键词】 槐耳; 菌质; 清膏; 生物反应调节剂
【英文关键词】 Trametes robiniophila Murr.; Fungal substance; Clear paste; Biological response modifier

【文献出处】 食用菌学报,Acta Edulis Fungi,编辑部邮箱,1995年01期 【DOI】CNKI:SUN:SYJB.0.1995-01-004