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Crude Polysaccharides Extracted From Several Medicinal Fungi Exhibit Hypoglycemic Functions in Mice


【发布日期】:2010-05-17

TAO Meihua1; 2; ZHANG Weimin1; PAN Qingling1; LI Haohua1; WANG Lei1; TAN Yuzhi31Guangdong Institute of Microbiology; Guangzhou; Guangdong 510070; China; 2Guangdong Pharmaceutical University; Guangzhou; Guangdong 510006; China; 3South China Botanical Garden; Chinese Academy of Sciences; Guangzhou; Guangdong 510650; China

【中文摘要】 The hypoglycemic effects of crude polysaccharides extracted from five medicinal fungi were evaluated using alloxan-induced diabetic mice.High(1 g/kg)and low(0.5 g/kg)doses of polysaccharides extracted from Cordyceps taii and C.memorabilis caused significant(P<0.01)decreases in mice blood sugar levels.Polysaccharides from Ganoderma lucidum and C.militaris fruit bodies both exhibited weak hypoglycemic effects at significance levels of P<0.01 and P<0.05 for high and low doses,respectively....更多Polysaccharide extracted from mycelium of a Phellinus sp.was significantly(P<0.05)hypoglycemic at higher dose levels but lower doses had no effect. 还原

【英文摘要】 The hypoglycemic effects of crude polysaccharides extracted from five medicinal fungi were evaluated using alloxan-induced diabetic mice.High(1 g/kg)and low(0.5 g/kg)doses of polysaccharides extracted from Cordyceps taii and C.memorabilis caused significant(P<0.01)decreases in mice blood sugar levels.Polysaccharides from Ganoderma lucidum and C.militaris fruit bodies both exhibited weak hypoglycemic effects at significance levels of P<0.01 and P<0.05 for high and low doses,respectively.Polysaccharide extracted from mycelium of a Phellinus sp.was significantly(P<0.05)hypoglycemic at higher dose levels but lower doses had no effect.

【英文关键词】 Cordyceps; Phellinus; Ganoderma; polysaccharides; hypoglycemic effect
【基金】Sponsored by the Foundation of Guangdong Province(No.2005B333701016,2006B20201038)

【文献出处】 食用菌学报,Acta Edulis Fungi,编辑部邮箱,2009年01期 【DOI】CNKI:SUN:SYJB.0.2009-01-017

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